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Chlorpheniramine

Chlorpheniramine is an antihistamine medication used to treat various allergic reactions, including seasonal allergies, allergic rhinitis, hives, and allergic conjunctivitis. It functions by inhibiting the impact of histamine, a chemical the body generates in an allergic reaction. Chlorpheniramine is additionally effective in helping treat typical cold symptoms such as sinus infection and sneezing. It can also reduce irritation caused by eczema and other skin problems. However, it is important to note that Chlorpheniramine is not a cure for allergies and should be used only to relieve symptoms.

Uses of Chlorpheniramine

Here are some of the common uses of Chlorpheniramine:

  • Respiratory Infections: Effectively alleviates symptoms associated with the common cold, flu, and other respiratory infections, providing relief from nasal congestion, sneezing, and related discomfort.
  • Hay Fever and Seasonal Allergies: Addresses symptoms of hay fever and seasonal allergies, countering issues like runny nose, itching, and watery eyes caused by environmental allergens.
  • Allergic Skin Conditions: Reduces symptoms of allergic skin conditions such as hives or itching, offering relief from the inflammatory response associated with these dermatological issues.
  • Insect Bites or Stings: Provides relief from allergic reactions triggered by insect bites or stings, mitigating symptoms like swelling and itching.
  • Urticaria (Hives): Used in the treatment of urticaria, a skin condition characterized by red, itchy, and swollen patches, addressing the discomfort caused by this allergic response.
  • Allergic Conjunctivitis: Treats allergic conjunctivitis, a condition marked by redness, itching, and watering of the eyes due to allergic triggers, contributing to ocular symptom relief.
  • Mild Sedative for Anxiety and Insomnia: In certain cases, Chlorpheniramine may be utilized as a mild sedative to address symptoms of anxiety and insomnia, imparting a calming effect.

It's important to note that Chlorpheniramine should only be used as directed by a healthcare professional and should not be taken longer than recommended.

How and when to take Chlorpheniramine?

Chlorpheniramine is taken orally, with or without food, and the dosage and frequency depend on age, medical condition, and response to treatment. Adults and children over 12 typically take 4mg every 4-6 hours, children between 6-12 years of age take 2 mg every 4-6 hours, and the dosage for children under 6 is determined by a healthcare provider. It is a short-term treatment for allergies, colds, and flu, and regular use for medical conditions should be discussed with a healthcare provider.

What are the side effects of Chlorpheniramine?

There could be some common side effects of Chlorpheniramine, such as:

  • Drowsiness and sedation are common side effects of Chlorpheniramine.
  • Dry mouth, throat, and nose are also common.
  • Other side effects include dizziness, headache, blurred vision, and nausea.
  • Some people may experience difficulty urinating or constipation.
  • Less common side effects include confusion, nervousness, excitability, and irritability.
  • Severe side effects such as difficulty breathing, irregular heartbeat, or seizures are rare but may occur.

What precautions should be taken?

The following are some precautions to consider when taking Chlorpheniramine:

  • Consult your doctor before taking Chlorpheniramine if you have any pre-existing medical conditions such as liver or kidney disease, glaucoma, or an enlarged prostate.
  • Avoid consuming alcohol while taking Chlorpheniramine, as it may increase the drowsiness caused by the medication.
  • Consult your doctor when you're pregnant or nursing before taking Chlorpheniramine, as its safety during pregnancy and breastfeeding is not well-established.

Dosing for Chlorpheniramine

The dosing for Chlorpheniramine can vary depending on the specific formulation and the age of the individual. It's important to follow the recommended dosage instructions provided by a healthcare professional or as indicated on the product packaging. Here are general guidelines for different formulations:

Chlorpheniramine Immediate-Release Tablets:

  • Adults and children age 12 years and up:
    • Typical dose: 4 mg every 4 to 6 hours.
    • Maximum daily dose: Do not exceed 24 mg in a 24-hour period.
  • Children age 6 to under 12 years:
    • Typical dose: 2 mg (half a tablet) every 4 to 6 hours.
    • Maximum daily dose: Do not exceed 12 mg in a 24-hour period.
  • Children age less than 6 years:
    • Dosage should be determined in consultation with a healthcare provider.

Chlorpheniramine Extended-Release Tablets:

  • Adults and children age 12 years and up:
    • Typical dose: 12 mg every 12 hours.
    • Maximum daily dose: Do not exceed 24 mg in a 24-hour period.
  • Children age less than 12 years:
    • Dosage should be determined in consultation with a healthcare provider.

It's crucial to use the correct measuring device, follow age-appropriate dosages, and consult with a healthcare professional or pharmacist, especially in the case of children, to ensure safe and effective use.

What if I missed the dose of Chlorpheniramine?

If you miss a dose of Chlorpheniramine, take it as soon as you remember. If your next dose approaches, skip the missed dosage and follow your regular dosing schedule. Do not duplicate the prescription to compensate for a missing one. If you are unsure what to do, consult your healthcare provider.

What if there is an overdose of Chlorpheniramine?

An overdose of Chlorpheniramine can cause serious side effects and may require immediate medical attention. Symptoms of an overdose may include confusion, drowsiness, difficulty breathing, seizures, hallucinations, and an irregular heartbeat. If you or anyone you know has a Chlorpheniramine overdose, seek medical attention immediately or call the local emergency number. It is important to never exceed the recommended dose of Chlorpheniramine without consulting a healthcare professional.

What are the storage conditions for Chlorpheniramine?

Chlorpheniramine should be stored in a firmly sealed container, stored at room temperature from 20 - 25C (68 - 77F). Keeping Chlorpheniramine out of the reach of children and pets is important. Do not use Chlorpheniramine after the expiration date printed on the label. If you are unsure how to store Chlorpheniramine, consult your healthcare provider or pharmacist.

Caution with other medicine

Chlorpheniramine may interact with other medications, including:

  • Antidepressants
  • Sedatives or tranquilizers
  • Alcohol
  • Other antihistamines
  • Pain medications

How quickly does Chlorpheniramine show results?

Chlorpheniramine typically starts to show its effects within 30 minutes of taking it, with peak effects seen after about 1 to 2 hours. The duration of action of the medication is around 4 to 6 hours. However, the start and duration of the effect may vary based on individual characteristics such as age, weight, and the complexity of the ailment being treated. Sticking to the specified dose and not surpassing it is critical, as doing so increases the chance of negative effects. See a doctor if your pain persists or intensifies despite taking Chlorpheniramine.

Chlorpheniramine Vs Cetirizine

 

Chlorpheniramine 

Cetirizine

Composition

Chlorpheniramine is a first-generation antihistamine.

Cetirizine is a second-generation antihistamine.

Uses

Chlorpheniramine treats sneezing, itching, runny nose, common cold, and hay fever.

Cetirizine treats hay fever, hives, itching, common cold, and respiratory allergies.

Side Effects

Chlorpheniramine may cause drowsiness, dry mouth, constipation, blurred vision, and difficulty urinating.

Cetirizine may cause drowsiness (less likely than Chlorpheniramine), dry mouth, headache, and stomach pain.

Faqs

1. Are Cetirizine And Chlorpheniramine the Same?

No, Cetirizine and Chlorpheniramine are different antihistamines. While both are used to treat allergy symptoms, they have different chemical structures and may have variations in onset, duration, and side effects. It's crucial to follow the specific guidance provided by a healthcare professional for each medication.

2. What is chlorpheniramine used for?

Chlorpheniramine is an antihistamine commonly used to alleviate symptoms associated with various allergic reactions. It is utilized for conditions such as seasonal allergies, hay fever, hives, allergic conjunctivitis, and symptoms of the common cold, including respiratory infections.

3. Are there any food or drink restrictions while taking Dextromethorphan?

Generally, there are no specific food or drink restrictions while taking Dextromethorphan. However, it's advisable to read the product label and follow any instructions provided. Some formulations may contain additional ingredients that could have specific recommendations regarding food or drink.

4. Is Dextromethorphan addictive?

Dextromethorphan itself is not considered addictive when used as directed. It is an over-the-counter cough suppressant that works on the cough reflex in the brain. However, misuse of products containing dextromethorphan, such as taking large doses for recreational purposes, can lead to adverse effects and may be associated with dependency. It's crucial to use this medication as directed and to seek medical advice if there are concerns about its use.

5. Is Chlorpheniramine Anti-Inflammatory?

While Chlorpheniramine is effective in reducing symptoms associated with allergic reactions, it is not considered a primary anti-inflammatory medication. It works by blocking the effects of histamine, a chemical involved in allergic responses, but it does not have the same anti-inflammatory properties as corticosteroids or other specific anti-inflammatory drugs. If anti-inflammatory effects are needed, other medications may be more appropriate, and a healthcare professional should be consulted for personalized advice.

References:

https://medlineplus.gov/druginfo/meds/a682543 https://www.drugs.com/dosage/chlorpheniramine. https://www.mayoclinic.org/drugs-supplements/chlorpheniramine-oral-route/proper-use/drg-20073321.

Disclaimer: The information provided here is not meant to substitute an advice from a healthcare professional. The information is not intended to cover all the possible uses, side-effects, precautions, and drug interactions. This information is not intended to suggest that using a specific drug is suitable, safe, or efficient for you or anyone else. The absence of any information or warning regarding the drug should not be interpreted as an implicit guarantee from the organisation. We strongly advise you to consult a doctor if you have any concerns about the drug and never use the medication without a doctor’s prescription.