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Updated on 13 October 2023
C-reactive protein, or CRP, is a protein produced and released by the liver into the bloodstream in response to inflammation. The CRP test is a nonspecific serological diagnostic test, serving as a marker for inflammation in the body. Read on to learn more about how much C reactive protein is dangerous and when high CRP levels become a concern.
CRP, or C-reactive protein, is a protein produced by the liver and released in response to inflammation in any part of the body. It functions as a defence mechanism against injuries, infections, and various autoimmune conditions, while also serving as a marker for cardiovascular diseases and cancer. The level of CRP rises rapidly in the bloodstream during inflammatory conditions. Therefore, measuring CRP levels in the blood can help detect inflammation or monitor the progress of an inflammatory condition or its treatment.
It is normal to have low CRP levels in the blood at all times. Moderate to high CRP levels can indicate infection or other inflammatory conditions. However, significantly elevated CRP levels can be a cause for concern. There can be various reasons to understand how much hs CRP level is dangerous.
The level of CRP in the blood may vary depending on the underlying cause of inflammation. Moderate to severe elevations in CRP levels may indicate inflammation. To determine how high a CRP level is and whether it signifies an infection or poses a danger, one can compare the obtained CRP level to the provided reference ranges.
Normal CRP Level: Typically, a CRP level of less than 10 mg/L in the blood is considered safe.
Moderate Elevation: CRP level elevation may be considered moderate if it is between 1-10 mg/dL. Such elevation may be due to:
Marked Elevation: Having more than 10 mg/dL level of CRP in the blood may be considered as marked elevation which may be caused by:
High Elevation: Higher than 50 mg/dL of CRP may be considered as high or severe elevation. Usually, such high levels of CRP in the blood has been associated with acute bacterial infection.
High-sensitivity C-reactive protein or hs-CRP is a diagnostic test which is more sensitive than a standard CRP test. The hs-CRP test can detect smaller increases in CRP levels better than a standard CRP test. The hs-CRP test helps to determine the risk of coronary artery diseases. A high level of hs-CRP has been linked to an increased risk of heart attack.
While the hs-CRP test is helpful for people who have a 10% to 20% chance of heart attack, this test is not for everyone. This test does not explain the cause of inflammation, therefore, it is possible to have a high hs-CRP level without having any risk of heart attacks.
Reference ranges for the hs-CRP test are usually given as follows:
A hs-CRP test is not the only standard test for determining the chance of heart disease. If the level of hs-CRP is high, other test results have to be considered for evaluate the risk of heart diseases
Having a slightly higher-than-normal CRP level is not always a bad sign. In certain conditions, it is normal to have higher than standard level of CRP such as:
Oftentimes, a CRP blood test is considered an indicator of inflammation. If CRP levels are high, other relevant tests may be recommended to be performed to diagnose any suspected condition or understand why the CRP levels are high.
CRP Level (mg/L) |
Interpretation |
Less than 1 |
Low risk of cardiovascular disease |
1 - 3 |
Average risk |
3 - 10 |
Moderate risk |
Greater than 10 |
High risk
|
CRP, or C-reactive protein, is a biomarker commonly used in medical settings to assess levels of inflammation in the body. Here’s how CRP is utilized in diagnosing inflammation and infection:
If you have a high CRP (C-reactive protein) level, here’s what you should do:
Here are steps you can take to lower your CRP levels through diet and lifestyle modifications:
The CRP levels may vary over seasons or as a person ages. A number of factors affect the level of CRP in an individual. Mostly, having slightly elevated levels of CRP is not something to be worried about. The CRP test is usually prescribed by a doctor only if they want to get a comprehensive understanding of certain symptoms or to track the progress of treatments.
If CRP levels in the blood are high, it may mean that there is an inflammation in the body caused by an infection, injury, or by chronic or acute health conditions which may require proper medical treatment.
Bacterial, viral, or fungal infections often cause inflammation which leads to high CRP levels. These infections may be uncomplicated infections, particularly those caused by adenovirus and influenza virus. However, having a marked elevation of CRP levels may be indicative of acute bacterial infection.
A CRP test is typically ordered by a doctor to check for inflammation or if they suspect any condition which is causing inflammation. Higher than 20 mg/dL of CRP may be a cause of concern.
A critical level of CRP typically refers to levels greater than 10 mg/L. This indicates significant inflammation and may suggest acute conditions such as severe infections, autoimmune flare-ups, or cardiovascular risks.
You can get your CRP levels tested through a simple blood test. Consult your healthcare provider who can order the test for you. It's usually done in a laboratory or clinic.
You may need a CRP test if you have symptoms of inflammation, such as fever, pain, or swelling, or if you are at risk for cardiovascular disease or have an autoimmune condition. It helps diagnose and monitor various inflammatory conditions.
During a CRP test, a healthcare professional will draw a blood sample from a vein in your arm. The procedure is quick and involves minimal discomfort, similar to a routine blood draw.
Yes, if your CRP level is abnormal, it's important to be concerned and take action. An abnormal CRP level typically indicates inflammation in your body, which could be due to infections, autoimmune diseases, or other health issues. It's crucial to follow up with your healthcare provider to determine the underlying cause and receive appropriate treatment. Monitoring and managing your CRP levels can help in maintaining overall health and preventing complications associated with chronic inflammation.
The recovery time for high CRP levels depends on the underlying cause. Once the cause is identified and treated effectively (such as with antibiotics for infections or anti-inflammatory medications for inflammatory conditions), CRP levels can decrease over days to weeks.
Several infections can cause high CRP levels, including bacterial infections such as pneumonia, urinary tract infections (UTIs), and bacterial meningitis. Viral infections may also cause a temporary rise in CRP, although typically not as high as with bacterial infections.
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